2015.02.13 - News from the centers

AG Löhning: "T helper cells have a quantitative memory for cytokine expression"

Publication in the journal "Immunity"

The group of Max Löhning (deputy director RCIS) found out that T helper cells produce different amounts of a certain cytokine. Some T helper cells secrete high amounts of this immune messenger and others produce only low quantities. Individual T helper cells acquire a stable quantitative memory for cytokine expression, i.e. in later reactivations; they always produce a similar amount of the given cytokine again, resulting in a stable heterogeneity within a population of differentiated T helper cells. 

 

Please find detailed informationOpens external link in current window here.

 

(Helmstetter et al., 2015, Immunity 42, 108–122 January 20, 2015)

 

 

Contact:

Prof. Dr. Max Löhning

Medizinische Klinik mit Schwerpunkt Rheumatologie und Klinische Immunologie
CharitéUniversitätsmedizin Berlin
Deutsches Rheuma-Forschungszentrum 
phone: +49 30 2846 0760



back to list

More news...

...from the Charité can be found here.

Contact

Prof. Dr. Birgit Sawitzki
Leitung des RCi³
t: +49 30 450 524 136
Prof. Dr. Andreas Christian Hocke
Redaktionelle Gestaltung
t: +49 30 450 553 477
Das ist das RCi3 Logo